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中文
CRISPR/Cas9技术将人类转铁蛋白受体上皮域的编码序列插入到特定位置，形成了一种嵌合的人鼠共通的转铁蛋白受体，它在内源性启动子的调控下表达。这种设计保留了原鼠转铁蛋白配体结合域，并保留了Tfrc的大部分内含子，以减少蛋白质表达和功能可能的失调。(来源：J:325423)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
