CRISPR/Cas9技术被用来在exon 2的79,841,638到79,842,251位置插入一个早终止密码子,以预测会导致非翻译性mRNA降解和无蛋白产生。这在三条线中得到了实现。(来源:J:325206)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count