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中文
在exon 2的GAG密码子位置50被替换为lysine（AAG），通过sgRNA和ssODN模板，使用了CRISPR/Cas9技术。这种在编码肽的EMO（NF kappa B必需调节因子）区域的变异，复制了与正常眼压青光眼（NTG）相关的人类正常变异（J:303304）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
