这些小鼠体内Stat3基因的18-20号外显子周围带有loxP位点,通过与表达Cre重组酶的品系杂交,可以用来在特定组织中条件性地抑制Stat3基因的表达。Stat3-Flox小鼠(Stock No. NM-CKO-200050,它们的loxP位点位于12-14号外显子)也被提及(J:238766)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
插入
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1
8
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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