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中文
建立了一条Mettl5的条件敲除线，其中第2外显子被敲除，通过Cre的表达会引发第2外显子的缺失，产生框移突变。构建中包含的FRT引导的诺卡因 cassette 在实验中被剔除了。该构建通过电穿孔技术将gRNA/Cas9蛋白转入了C57bl/6和129S6杂交F1代的ES细胞中。（来源：J:322368）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
