CRISPR定向插入的loxP座位于ENSMUSE00000183218外显子周围,位置在染色体4的132,335,981和132,335,170(GRCh38),通过Cre介导的重组,去除了含有的floxed外显子。(来源:J:322048)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count