在exon 1的上游插入了一个loxP位点和FRT引导的neo cassette,通过同源重组,再在exon 1的下游插入了一个loxP位点。Flp介导的重组移除了neo cassette,使得exon 1被标记为可删除的。(来源:J:316296)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count