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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gt(ROSA)26Sor
tm1.1(GSDMB_i2,-EGFP)Gmbu
Alias:
R26-GB2
GB2
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基础信息
表型特征
文献报道
在该位置插入了由loxP引导的PGK-neomycin-STOP cassette、人Gasdermin B亚型2的HA标签、IRE序列和EGFP。随后,通过Cre介导的重组去除了neomycin-STOP cassette(来源:J:321835)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
7256400
C57BL/6 x 129
Targeted
插入
--
--
--
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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