CRISPR/cas9基因编辑通过在exon 2上游(GGACCTGTAGTTTGAAATTC和GAATTTCAAACTACAGGTCC)以及下游(AGTAAGGATGATTGCAGCCC和GCTCACACAGTTTCCTGGCC)使用引导RNA,插入loxP位点。(来源:J:94077)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count