CRISPR/cas9 genome editing is used to delete exon 3. Guide RNAs were selected to target upstream [GACCAGATGAGGCTAGCTAA ; GCCCATTAGCTAGCCTCATC] and downstream [GTTTATAGATTGTTGGCCAT ; TATCTTCTCTTTTCTGCCCA] of exon 3. Progeny were screened by DNA sequencing of the targeted region, which identified a founder harboring a complete loss of exon3. (J:101977)