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CRISPR/cas9基因编辑用来去除exon 3，选择的导向RNA针对exon 3上游的[AGCCAGTCCGCCACTAAAAT]和下游的[CCCCCCGGTTACTTGTGATT; CACCTAATCACAAGTAACCG]区域。后代通过针对这些区域的DNA测序筛选，发现 founder 3628携带有exon 3的完全丢失。(来源：J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
