CRISPR/cas9 genome editing used a signal guide RNA designed to introduce a 115 nucleotide deletion mutation in exon 10. The deletion is (CTGCTCCTGCTCTAGaaaagctacgtgcc/del115/acgctcatgtttggacagcgGTCAGTATCAGA; lower case nucleotides are exon 10 sequences with flanking intronic DNA in upper case). (J:101977)