CRISPR/Cas9基因编辑通过crRNAs在exon 2的上游(CCTTCAGCAGGTACTATCCA; CCCTTCAGCAGGTACTATCC)和下游(CTGGCCATGCTCAGGCCCTA; ATGCTCAGGCCCTAGGGATG)位置插入了loxP位点。来源:(J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count