在exon 2的上游插入了FRT-flanked neomycin cassette和一个loxP位点,而在exon 3的下游则插入了另一个loxP位点。通过Cre介导的重组,去除了exons 2和3。这个等位基因包含了neomycin cassette。(来源:J:253840)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count