CRISPR/Cas9技术在exon 4产生了1个碱基和10个碱基的缺失。 Western blot和免疫荧光分析确认了纯合突变小鼠睾丸中蛋白表达的缺失。(来源:J:319365)
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CRISPR/Cas9 technology generated a 1-bp and 10-bp deletion in exon 4. Western blot and immunofluorescence analysis confirmed the absence of protein expression in testes of homozygous mutant mice. (J:319365)