这个靶向载体被设计成在Loxl1基因序列的exon1上游插入一个loxP和一个由FRT引导的pGK-Neomycin-polyA插件,然后在exon1之后再插入一个loxP。通过Flp重组酶,neo cassette会被剔除。(来源:J:317721)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Targeted
插入
--
1
1
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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