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中文
在H19的内源性位点，通过CRISPR/Cas9基因编辑诱导了ICR序列的反转。这产生了三条携带正确反转ICR等位基因的转基因小鼠线，其中两条（线21和23）还带有人工酶位点。这是一来自这两只F0小鼠的突变小鼠品系23（J:317705）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
