Using homologous recombination in ES cells, a T2A-CreERT2 cassette was inserted in-frame immediately before the stop codon of the mouse Unc5b gene. The Frt-Neo-Frt cassette in the founder line was removed by breeding with Flpe deleter mice. (J:317073)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count