将一个带有p.C25S突变(以阻止肽的棕榈酰化)的鼠 sonic hedgehog 基因cDNA,置于鼠同源异型盒1(pair-related homeobox 1, Prrx1)驱动元件的控制下,使其在胚胎肢体芽发育中表达。(来源:J:89228)
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A mouse sonic hedgehog cDNA with a p.C25S mutation (to prevent palmitoylation of the peptide) was placed under the control of the mouse paired related homeobox 1 enhancer to drive its expression in embryonic limb buds. (J:89228)