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中文
这个靶向载体被设计用来替换基因的整个编码区域，用增强型绿色荧光蛋白（EGFP）序列替换。载体包含一个反向于基因的3' UTR中的FRT引导的诺卡因抗性（neo） cassette，带有polyApolyadenylation信号。通过FLP介导的重组，FRT引导的neo cassette被移除。免疫印迹分析证实了纯合突变小鼠各组织中无蛋白表达。（来源：J:316411）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
