将lysine的98位(AAA), 117位(AAG), 136位(AAG), 160位(AAG)和161位(AAG)编码替换为arginine,得到的等位基因分别为p.K98R, p.K117R, p.K136R, p.K160R和p.K161R。通过Cre介导的重组,移除了插入在内含子4的由loxP序列标记的诺卡因抗性基因元件。(来源:J:314680)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Nucleotide substitutions
--
1
65
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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