通过同源重组,使用传统的ES细胞策略,将包含CAG-rox-loxP-STOP-rox-H2B-eGFP-polyA-loxP-H2B-tdTomato-wpre-polyA-Frt-Neo-Frt序列的目标片段插入Rosa26基因座的第1内含子中。(来源:J:314889)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count