Sox4^tm1.1Cmo

Using homologous recombination in ES cells, the targeting vector inserted a single loxP into 5'UTR of the Sox4 gene, and a 3' loxP site followed by an frt-flanked neo cassette was inserted downstream of the single coding exon. The Neo cassette was removed by crossing to the Flp recombinase strain and deletion from the 3UTR was confirmed. (J:312333)