在TGR5基因的特殊TGR5外显子(去除了终止密码子)后面,通过插入一个Hemagglutinin(HA)标签,使其在框架内位置3,以制造一个标记的TGR5蛋白。接着,一个串联的Tomato(Tdt)标签被插入在一段间隔启动子(IRES)之后,作为TGR5表达水平的替代标记物,但具体细节未提供。(来源:J:313904)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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