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中文
通过CRISPR/Cas9技术，对酪氨酸密码子30(位于TAC)进行了替换，目标改变为谷氨酸(替换为GAA，p.Y30E)。使用的sgRNA是GAAGATTACCCGCCCGAGAA，而ssODN模板为CAGTATCTAGAGGACCTTGAAGATGTGGACCTCAAGAAATTCAAAATGCATTTGGAAGATGAACCGCCCGAGAAAGGCTGTATCCCAGTCCCCAGGGGCCAGATGGAGAAGGCAGATCACTTG。这种变异模拟了编码肽中该位置的磷酸化状态。(来源：J:291770)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
