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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(CD68-Edil3*)#Chav
Alias:
CD68-Del1-
E1-E3
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基础信息
表型特征
文献报道
这个转基因包含了以下组件:人类CD68启动子和内含子1,小鼠的EGF样重复序列和直径素I样域3的cDNA(去除了编码直径素I样域的序列),以及来源不明的poly(A)信号序列。这个等位基因在巨噬细胞中驱动了Edil3的截短表达。(来源:J:282521)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
6780174
C57BL/6NCrl
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插入
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1
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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