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中文
这个靶向构建插入了lox2272位点的第12个内含子，包含导致第495位氨基酸由asp替换为lys的突变核苷酸序列（E495K）。它包含了loxP位点、lox2272位点以及一个由FRT引导的诺卡因抗性基因座。通过Flp酶介导的重组移除了选择性基因座，而Cre介导的重组则恢复了修改后的第12个外显子。来源：(J:309176)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
