TALEN引导的基因组编辑产生了一个插入,将CTGAAGAATTT替换成TTTTTTATAATATAAAATAAG,位置在第13号外显子的Mre11交互域,共10个碱基的插入,导致了一个终止密码和缩短的蛋白质。(来源:J:251434)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
插入,基因内删除
--
1
16
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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