TALEN引导的基因组编辑产生了一个3个碱基的缺失(TTT),发生在Mre11交互域的第13外显子,这导致Mre11交互域中LKNFKKFKK序列的第一个苯丙氨酸被删除。(来源:J:251434)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
基因内删除
--
1
16
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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