靶向载体设计用于表达人AIRE与绿色荧光蛋白(GFP)连接的报告/Flag标签融合蛋白,后面跟着一个插入在第1和2外显子之间的诺卡因选择标记。通过Cre介导的重组,去除了含有的floxed neo cassette(来源:J:311532)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
3
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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