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中文
在第7外显子中，通过A到G的点突变(c.707A>G)，将天冬氨酸的密码子236替换为丝氨酸(p.N236S)。随后通过Cre介导的重组，移除了内含子11中的loxP位点所伴随的诺卡因抗性基因元件。这种突变存在于某些人类肿瘤和一些肿瘤性小鼠细胞系中。(来源：J:283471)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
