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中文
这个靶向构建插入了带有IRES-beta-geo融合序列的元件，周围是loxP位点，位于10号和11号外显子之间，11号外显子被替换为编码第316位氨基酸由ASP替换为ASN的序列（D316N）。通过Cre重组酶去除基因陷阱元件后，该等位基因表达出带有氨基酸替换的修改蛋白产品。(引用自J:104881和J:309735)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
