L1L2_Bact_P cassette被插入了染色体15的82,189,400位置,位于关键的exons2到4(基于GRCm39构建)的上游。该 cassette包含FRT位点、lacZ序列和一个loxP位点。FRT位点后面跟着由人类β-actin启动子驱动的诺卡因抗性基因、SV40polyA,然后是第二个FRT位点和第二个loxP位点。第三个loxP位点被插入在目标的exons2到4下游,位置在82,191,234。因此,关键的exons2到4被loxP位点所包裹。(来源:J:287069)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb
Targeted
插入
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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