CRISPR/Cas9基因编辑技术通过将Mlkl的短引导RNA(sg)RNA和Cas9 mRNA微注射到K14-Cre杂交产生的受精卵卵母细胞的核中,实现了Mlkl基因的突变产生。(来源:J:217312)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
基因内删除
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1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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