在第2个内含子插入了loxP位点和诺福克林(Neo)抗性基因座,同时在第8个内含子插入了F3位点和puromycin(普罗帕酮)抗性基因座,以及另一个loxP位点。随后通过flp介导的重组移除了这两个抗性基因座。通过western blot确认了这个等位基因不产生肽。参考文献:J:306481

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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