这个转基因包含了来自BACPAC资源中心Children's Hospital Oakland Research Institute的225kb BAC( RP11-388M20)的人类基因组FUS位点,带有loxP酶切位点,以及一个mCherry报告基因。第1和3号品系是通过定点突变独立插入了第15外显子的变异(c.1574C-T)。(来源:J:82809)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F1
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插入
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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