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中文
设计了一个靶向载体，用于将Frt-flanked诺卡因(neo)抗性基因座和loxP序列插入小鼠阿片受体(Oprm1)基因的第2外显子上游。构建物通过电穿孔技术导入了来自129S6/SvEv的胚胎干细胞(ES)克隆SCR012。产生的小鼠与Frt重组酶表达小鼠杂交，以消除neo基因座。这种小鼠品系允许通过Cre介导的方式删除第2外显子和第3外显子。(来源：J:291061)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
