Il17a^{tm2.1(EGFP/cre/ERT2)Flv}

A cassette encoding for a fusion protein consisting of the Internal Ribosome Entry Site (IRES), eGFP, Cre and human-modified Oestrogen Receptor (ERT2) (IGCE) was linked to a Frt-flanked neomycin (NEO) encoding cassette and inserted downstream of the translation stop codon in the mouse Il17a gene by targetted homologous recombination in ES cells. Germline transmitted mice were bred with germline Flippase expressing transgenic mice to remove the neomycin gene. (J:224098)