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中文
这个靶向载体包含一个SA.lox.Neo/Stop.lox-PDGFRaK.T2A.Flp元件，它取代了Pdgfra基因的2-4号外显子。PDGFRaK是经过点突变(D842V)的鼠源性Pdgfra基因的cDNA，使其成为持续激活状态。通过Cre介导的重组，去除了Pdgfratm1(flpo)Leol中含有的lox.Neo/Stop.lox片段，从而允许表达带有D842V点突变的激活型Pdgfra基因以及flpo重组酶。来源：(J:306160)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
