在小鼠Mecom基因的第1外显子的ATG密码子后立即通过同源重组,通过ES细胞引入了M2rtTA/IRES、loxP引导的GFP、polyA以及FRT引导的诺卡因筛选 cassette。产生的小鼠与表达Flp的 mice杂交,以去除筛选 cassette。(来源:J:292941)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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