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中文
这个靶向载体包含SA.lox.Neo/Stop.lox-PDGFRaK.T2A.Flp元件，它取代了Pdgfra基因的2-4号外显子。PDGFRaK是经过点突变(D842V)改造的鼠源性Pdgfra基因的cDNA，使其成为一种持续激活的版本。要表达这种带有D842V点突变的持续激活Pdgfra基因，需要通过Cre介导的重组。在Cre纯合状态下，它表现为野生型的无表达基因（J:306160）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
