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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Cldn11-cre/ERT2)151Tmak
Alias:
Cldn11-CreERT2
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基础信息
表型特征
文献报道
转基因中包含了BAC RP23-128D19,它与改良的雌激素受体(ERT2)的cre重组酶融合,并插入在起始密码子下游。生成了5个转基因原代品系,其中151号品系显示在淋巴瓣特异性的cre活性,用于后续研究(来源:J:308453)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
6727043
C57BL/6NTac
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插入
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3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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