在6a和6b外显子之间插入了一个lacZ-neo cassette,它被5'端的loxP和3'端的rox sites包裹。额外的rox site被置于6a上游,而loxP则位于6b下游,这样通过dre/rox重组可以去除6a和lacZ-neo cassette,通过cre/loxP重组则可移除6b和这个元件。来源:J:293382

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
插入
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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