在6a和6b外显子之间插入了一个lacZ-neo cassette,它被5'端的loxP和3'端的rox sites包裹。额外的rox site被置于6a上游,而loxP则位于6b下游,这样通过dre/rox重组可以去除6a和lacZ-neo cassette,通过cre/loxP重组则可移除6b和这个元件。来源:J:293382
Basic Information
(C57BL/6 x 129P2/OlaHsd)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count