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中文
通过C57BL/6J ES细胞的同源重组，将一个SA-3xFLAG-NLS-SpCas9-NLS-polyA-loxP-HSVtk-Neo-loxP的片段插入到Gt(ROSA)26Sor定位。靶向的ES细胞用于囊胚注射以获得转基因小鼠。随后，通过与Cre敲除小鼠杂交，去除了loxP-HSVtk-Neo-loxP片段。（来源：J:293207）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
