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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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基因编辑小鼠
Naa12
em1Gjl
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基础信息
表型特征
文献报道
CRISPR/Cas9导向的基因组编辑技术用于在Gm16286(UniProt Q9CQX6)基因的131-225位点创建一个95bp的缺失,这导致了密码子框架的移位,并在第67位产生了一个终止密码子(来源:J:308825)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
6723741
(C57BL/6 x DBA/2)F1 x C57BL/6J
Endonuclease-mediated
基因内删除
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1
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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