这个转基因插入包含以下组件:小鼠心肌肌球蛋白重链6α启动子序列,用于驱动心脏特异性的、经过突变(p.E40K,由G到A的点突变,导致第40位的谷氨酸被赖氨酸替换,c.118G>A)的 Constitutively Active 的小鼠胸腺瘤病毒 proto-oncogene 1 的cDNA,以及SV40内含子和poly(A)信号序列。(来源:J:258598)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
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插入
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1
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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