在Dre基因之前插入了一个剪接接受位点,然后是含有Ru486响应的激素结合域(hPR891)的突变型人类孕酮受体(PGR)。这个突变的PGR被连接到Dre序列的N端,后面跟着牛生长激素(BGH)的polyadenylation信号和PGK-Puro选择标记。载体通过ES细胞的同源重组插入到Gt(ROSA)26Sor位点。(来源:J:301641)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
插入
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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