在该位置插入了带有STOP cassette的敲除 cassette,以及一个突变的CD74等位基因cDNA,其中CLIP域的编码序列被替换为LCMV中免疫特异性较强的GP61-80肽序列。表达这个融合蛋白仅在Cre介导的重组后实现。(来源:J:306965)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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