Log In|Sign Up
中文
将改良型Cre重组酶(iCre)的编码序列、polyA序列和含loxP标记的诺卡因抗性基因簇插入Eomes基因的起始外显子1位点，导致5'编码区域约500bp的缺失。经过定向的ES细胞经过短暂的转染，用携带cre基因的质粒去除诺卡因抗性基因。这些细胞随后被用于生成生殖细胞嵌合体。(来源：J:306370)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
