Pomc^tm2.1Lowl

Mice with lox sites flanking exon III of the Pomc gene were generated using gene targeting in ES cells. The founders were bred to female mice bearing a germline-expressing Flpe recombinase transgene to obtain germ-line transmission of the floxed Pomc allele and to remove the frt-kanamycin-frt cassette. (J:303221)